Efektıvıtas Penggunaan Obat Antıhıpertensı Tunggal Angıotensın II Receptor Blockers (ARB) dan Calcıum Channel Blockers (CCB) pada Pasıen Stroke Iskemık dı Instalası Rawat Inap RSUD Dr. Soedırman Kebumen Tahun 2024

Alvina Dwi Nurhalisah; Muh Husnul  Khuluq; Ayu Nissa  Ainni; Tri Cahyani  Widiastuti

doi:10.57174/j.born.v5i2.185

Authors

Alvina Dwi Nurhalisah Faculty of Health Sciences, Muhammadiyah University of Gombong, Address Jalan Yos Sudarso No. 306, Gombong, Kebumen Regency, Central Java, Postal Code 54311, Country of Indonesia
Muh Husnul Khuluq Faculty of Health Sciences, Muhammadiyah University of Gombong, Address Jalan Yos Sudarso No. 306, Gombong, Kebumen Regency, Central Java, Postal Code 54311, Country of Indonesia
Ayu Nissa Ainni Faculty of Health Sciences, Muhammadiyah University of Gombong, Address Jalan Yos Sudarso No. 306, Gombong, Kebumen Regency, Central Java, Postal Code 54311, Country of Indonesia
Tri Cahyani Widiastuti Faculty of Health Sciences, Muhammadiyah University of Gombong, Address Jalan Yos Sudarso No. 306, Gombong, Kebumen Regency, Central Java, Postal Code 54311, Country of Indonesia

DOI:

https://doi.org/10.57174/j.born.v5i2.185

Keywords:

antihypertensive, ARB, CCB, ischemic stroke

Abstract

The increasing prevalence of ischemic stroke with hypertension demands optimal blood pressure control. At Dr. Soedirman Regional General Hospital, Calcium Channel Blockers (CCB) and Angiotensin II Receptor Blockers (ARB) are the main choices for monotherapy antihypertensive due to their effectiveness and mild side effect profiles. This study aimed to compare the effectiveness of ARB and CCB monotherapy in ischemic stroke patients admitted to the inpatient ward of Dr. Soedirman Regional General Hospital in 2024. The research employed a descriptive-analytic method with a cross-sectional design and retrospective data. A total of 112 patients meeting the inclusion criteria were selected using total sampling. Therapeutic effectiveness was analyzed using the Mann-Whitney test. The results showed that most patients were over 65 years old (64.29%) and male (50.89%). Both therapies effectively reduced blood pressure to the target of <140/90 mmHg. Statistical analysis revealed no significant difference between ARB and CCB use (p=0.995; p>0.05). The study concludes that ARB and CCB are equally effective in lowering blood pressure in ischemic stroke patients without significant differences. Further prospective studies are recommended to evaluate side effects, patient quality of life, and cost-effectiveness.

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