Vol. 2 No. 1 (2022): Volume 2 Issue 1 tahun 2022
● Articles: 5
● Editorial in chief: apt. Syuhada, M.Farm.
● Managing Editorial: apt. Irma Novrianti, M.Farm.Klin.
Full Issue
Articles
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Gambaran penggunaan antikoagulan pada pasien ST-Elevatıon Myocardıal Infarctıon (STEMI)
Abstract: 1331
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pdf (Indonesian): 4
Abstract
Penyakit jantung koroner merupakan salah satu penyakit penyebab kematian terbanyak. ST-segment elevation myocardial infarction (STEMI) salah satu klasifikasi dari Infark Miokard Akut (IMA). IMA timbul dari kerusakan permanen pada otot jantung karena suplai oksigen yang tidak mencukupi. Adanya IMA dapat merusak fungsi sistol dan diastol, serta menambah kejadian yang tidak diharapkan seperti aritmia pada pasien. Tujuan dari penelitian ini adalah melihat penggunaan antikoagulan pada pasien STEMI yang menggunakan terapi fibrinolitik. Penelitian ini bersifat deskriptif yang dilakukan secara retrospektif dengan melihat catatan medis pasien STEMI yang menjalani rawat inap di RS “X” kota Tarakan periode 2017-2018. Hasil penelitian menunjukan bahwa semua pasien STEMI menerima terapi antikoagulan. Sebanyak 92,31 % menggunakan enoxaparin dan 7,69 % pasien menggunaan fondaparinux dengan karakteristik pasien sebanyak 12 penyakit penyerta. Pemberian antikoagulan pada pasien STEMI membantu menjaga kondisi arteri setelah proses reperfusi ketika telah diberikan fibrinolitik sehingga tidak menyebabkan terjadinya reoklusi.
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Pengelolaan sedıaan metadon pada Program Terapı Rumatan Metadon (PTRM) dı satelıt pelayanan PTRM
Abstract: 297
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pdf (Indonesian): 4
Abstract
Methadone is a type of synthetic narcotic that is used as substitution therapy in the Methadone Maintenance Therapy Program (MMTP). Therefore, methadone must be treated as narcotics in general. Pharmacists in MMTP have responsibility for the management of methadone. This study aims to evaluate the suitability of the management of methadone preparations at the MMTP satellite service in the Special Region of Yogyakarta (DIY) based on the MMTP guidelines issued by the Ministry of Health which include requests, storage, dispensing, and reporting of methadone use. This study is a mixed-methods study (qualitative and quantitative) with prospective data collection. The quantitative measurement instrument in the study was in the form of a checklist table for the suitability of methadone management based on applicable guidelines. Qualitative data sourced from interviews with MMTP officers. The results of this study indicate that the demand, storage, and reporting of the use of methadone are in accordance with the MMTP service guidelines. However, for the dispensing of methadone on the MMTP service satellites, it is still carried out by health workers other than pharmacists.
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Laporan kasus selulitis pedis pada diabetes melitus tipe 2 dengan terapi antibiotik dan insulin
Abstract: 3028
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pdf (Indonesian): 4
Abstract
Diabetes mellitus (DM) is called the silent killer which can cause microvascular and macrovascular complications. Cellulitis is a form of microvascular complication of uncontrolled DM. A 49-year-old female patient came to the hospital with complaints of sores and pain in the right big toe. The patient has a history of type 2 diabetes mellitus, with the result of a current blood sugar level of 582 mg/dL. The patient received insulin therapy novorapid® and levemir®, paracetamol injection, ceftriaxone injection, metronidazole injection and amlodipine. From the results of monitoring drug therapy, administration of combination therapy with antibiotics and insulin is the right and safe choice of therapy in overcoming gangrenous infections with uncontrolled blood glucose conditions. However, in monitoring drug therapy, it was found that there was a potential for minor drug interactions between metronidazole and paracetamol. Metronidazole can increase the level or effect of paracetamol by affecting the metabolism of the liver enzyme CYP2E1 so there must be a delay in administration. Topical antibiotics should be considered in the long-term treatment of complications of cellulitis pedis in type 2 DM patients.
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Description of Adolescent Knowledge and Behavior About Obesity in SMA Negeri 1 Tarakan City
Abstract: 187
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pdf (Indonesian): 4
Abstract
Obesity is one of the problems of adolescents who are influenced by factors such as poor eating patterns, unhealthy food choices, and lack of physical activity, thus triggering the accumulation of excess fat in the body, which can lead to the emergence of various types of non-communicable diseases and is one of the causes of death worldwide. This research was conducted to describe the knowledge and behavior of adolescents about obesity at SMA Negeri 1 Tarakan City. This research is descriptive. Sampling was carried out by non-probability sampling with quota sampling with 53 respondents. The results showed that the characteristics of the respondents based on age were the most in the 17-year category, with 28 (52.4%) respondents. Characteristics based on BMI showed that the majority had the most BMI obesity, as many as 27 (50.9) respondents. Characteristics based on genetics (heredity) obtained the most results in the category without a history of obesity, as many as 41 (77.4%) respondents, characteristics of respondents based on knowledge obtained partial results 46 (86.8%) have good knowledge, 3 (5.7%) have sufficient knowledge, 4 (7.5%) respondents lack knowledge, and the characteristics of respondents based on eating patterns show partial results on bad eating patterns of 38 ( 71.7%) of respondents. The conclusion of this study shows that adolescents aged 17 years have good knowledge about obesity and eating behavior.
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Description of the Use of Antıhıpertensı in ST-Elevatıon Myocardıal Infractıon Patients
Abstract: 146
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pdf (Indonesian): 4
Abstract
ST-Elevation Myocardial Infraction (STEMI) is caused by several factors, mainly due to cardiovascular disorders. There are several complaints from STEMI, such as chest pain, elevated enzymes, and ST elevation on electrocardiogram examination. One of the major factors in the occurrence of STEMI is hypertension. The more severe the hypertension condition will slowly damage the blood vessel walls causing swelling, which leads to STEMI. This study aimed to see the use of antihypertensives in stemmy patients who were using fibrinolytic therapy. This research method is descriptive retrospective by looking at the medical records of STEMI patients who received antihypertensive treatment at the Emergency Room (ER) and were hospitalized at Tarakan City "X" Hospital for the 2017-2018 period. Based on the research, it was found that 55 patients used antihypertensives. The highest classification of blood pressure when admitted to the hospital was in stage II conditions based on JNC VII in 15 people (27.28%), and the classification of blood pressure when leaving the hospital was found to be in normal condition in 23 people (41.82%). The most antihypertensive used in "X" Hospital in Tarakan city is the ACE-Inhibitor group, namely captopril, with a percentage of 10.90% in the ER, and the Beta blocker group, namely bisoprolol fumarate with a percentage of 65.46% in the Inpatient Room.
