Vol. 4 No. 2 (2024): Volume 4 Issue 2 tahun 2024
● Articles: 5
● Editorial in chief: apt. Syuhada, M.Farm.
● Managing Editorial: apt. Benazir Evita Rukaya, M.Farm.
Articles
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Phytochemical Screening of Ethanol Extract of Tarap Fruit Seeds (Artocarpus odoratissimus)
Abstract: 373
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PDF 37-46 (Indonesian): 226
Abstract
Tarap fruit (Artocarpus odoratissimus), also known as "terap", is a type of fruit that grows in various tropical regions in Southeast Asia. because almost every part of the fruit has pharmacological properties, it is often used as an ingredient in traditional medicine. The plant has been part of many different cultures for a long time, used as a food source, and is widely used to help improve health. This study aims to conduct phytochemical screening on tarap fruit seed extract to identify the secondary metabolite compounds contained in it with a focus on compounds such as polyphenols, alkaloids, tannins, saponins, steroids, and terpenoids. This study uses a qualitative experimental method to analyze phytochemistry by color test using various reagents from tarap fruit seed extract, to identify secondary metabolite compounds in the plant. Tarap fruit seed samples were obtained from local fruit sellers in Tarakan. Extraction of tarap fruit seeds was carried out using 96% ethanol with maceration technique, then examined the content of polyphenols, alkaloids, tannins, saponins, steroids and terpenoids. The results showed the presence of several secondary metabolites in tarap fruit seed extract, proving the content of polyphenols, alkaloids, saponins, and terpenoids, while tannins and steroids could not be detected. The conclusion is that the ethanol extract of tarap fruit seeds (Artocarpus odoratissimus) contains polyphenols, alkaloids, saponins, and terpenoids.
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Overview of Over-the-Counter Medicine Sales and Investment at "X" Pharmacy, Karang Anyar District, Tarakan City Using ABC Analysis Year 2022
Abstract: 246
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PDF 47-54 (Indonesian): 161
Abstract
Drug management includes planning drug availability, including type, amount, quality, and quantity, to increase efficiency. One method used in drug planning is ABC or Pareto. This research aims to look at the sales and investment picture of over-the-counter OTC drugs at Pharmacy "X" using ABC analysis based on sales data for 2022. This research is a quantitative descriptive research, the retrospective data obtained was analyzed using Microsoft Excel® with the ABC method. The OTC drug data obtained was then classified into 3 groups, namely A, B, and C with cumulative percentages for groups A (70%), B (20%), and C (10%) of the sales or investment value. Based on the results of the analysis, it was found that drugs with sales value in group A contained 147 items of medicine with an investment value of Rp. 381,662,590 (69.91%). Meanwhile, group B contained 164 medicinal items with an investment value of Rp. 109,472,850 (20.05%). Meanwhile, for group C there are 305 items of medicine with an investment value of Rp. 54,790,100 (10.04%). The research conclusion shows that category A dominates the investment value, while category C has a lower investment contribution even though the number of types of drugs is greater.
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Overview of Sales and Investment of Generık Drugs "X" Pharmacy, Kampung Satu District, Tarakan City Using ABC Analysis in 2022
Abstract: 243
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PDF 55-60 (Indonesian): 104
Abstract
Pharmacies as health facilities and businesses, require good management to avoid shortages or excess stock of medicines. This research aims to optimize generic drug inventory management at pharmacy "X" using the ABC method. Using a quantitative and retrospective descriptive approach, generic drug sales data for the period January- December 2022 were analyzed. As a result, Group A consisted of 23 drug items with a total sales transaction of 5,877 (69.89%), Group B consisted of 28 drug items with a total sales transaction of 1,654 (19.67%), and Group C consisted of 71 items with the number of sales transactions was 878 (10.44%). In terms of investment value, Group A consists of 31 medicinal items with an investment value of Rp. 39,058,600 (69.63% of the total), Group B consists of 33 medicinal items with an investment value of Rp. 11,290,000 (20.13% of the total), and Group C consists of 58 medicinal items with an investment value of Rp. 5,743,300 (10.24% of the total). The ABC method can optimize generic drug inventory management at pharmacy “X”, enable prioritization based on sales frequency and investment value, and increase efficiency.
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Qualitative Analysis of Rhodamine B in Eyeshadows Circulating in Cosmetic Stores in Tarakan City
Abstract: 246
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PDF 61-66 (Indonesian): 259
Abstract
Both adults and teenagers often use eyeshadow as a common cosmetic. The paint and textile industry often uses a red synthetic dye known as rhodamine B. Apart from having carcinogenic properties, continued use of rhodamine B can cause liver problems and gastrointestinal irritation which has the potential to hurt health. This research aims to answer the problem, of whether or not eyeshadow preparations sold in Tarakan City beauty shops contain Rhodamine B. The method in this research uses a wool thread technique and a rhodamine B rapid test kit to carry out qualitative analysis using eleven samples. The results showed that of the eleven eyeshadow samples examined at the Tarakan City cosmetics shop, three samples experienced a color change from red to dark red or purplish. Two of the eyeshadows are not registered, while one is registered with BPOM. Based on these findings, it can be concluded that three of the eleven eyeshadow samples tested positive for rhodamine B.
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Identification of Gram-Negative Pathogenic Bacteria in Microbiology Practical Equipment at the Central Laboratory of Stikes Maharani, Malang
Abstract: 1382
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PDF 67-80 (Indonesian): 1967
Abstract
Stacks of laboratory equipment and lack of routine sterilization can contribute to the growth and contamination of pathogenic bacteria. This research aimed to determine the types of gram-negative pathogenic bacteria present in the microbiology practicum equipment at the Central STIKes Maharani Malang Laboratory. This type of research is descriptive research with an analytical research design. The sampling technique uses purposive sampling. This research involves taking swab samples on the surface of practical microbiology equipment, isolating bacterial colonies using MCA (Mac Conkey Agar) media, making pure cultures on MCA slanted agar media, macroscopic observations, and biochemical tests. Bacteria were grown on MCA media for 2x24 hours. The results of research using gram staining showed gram-negative bacteria, rod-shaped, spread, and red. Biochemical tests showed glucose (+g), lactose (+), mannitol (+), maltose (+), sucrose (+), H2S (-), indole (-), Mr (Methyl Red) (-), Vp ( Voges Praskaeur) (+), citrate (+), motility (-), the bacterial species Klebsiella pneumoniae was found. The second result shows glucose (+g), lactose (+), mannitol (+), maltose (+), sucrose (+), H2S (-), indole (+), Mr (Methyl Red) (+), Vp ( Voges Praskaeur) (-), citrate (-), motility (-), found Escherichia coli bacterial species. This study concluded that it was found that gram-negative bacteria were rod-shaped, spread, and red. Meanwhile, from biochemical tests using glucose, lactose, mannitol, maltose, sucrose, ındol, MR, VP, and citrate, Klebsiella pneumoniae and Escherichia coli bacteria were found.
